View abstract. View abstract. View abstract. Are there any side effects to taking astragalus root? View abstract. Leehey, D. J., Casini, T., and Massey, D. Remission of membranous nephropathy after therapy with Astragalus membranaceus. 2006;26(6):504-507. However, more studies. Yong WU, Yand OU, Ping J, Ke WU, and et al. Wei, L., Su, Z. J., and Guan, F. S. Randomized double-blind controlled study of therapeutic effects of Astragalus injection on children with cerebral palsy. Never go off of your diabetes medication until you speak to your doctor. It is created by eHealthMe based on reports of 5 people who take the same drugs from the FDA, and is updated regularly. A., and Abrams, D. I. A tea containing 6 to 12 g of dried root in 12 ounces of water can be used three times daily, and 500 to 1,000 mg of powdered root is taken three to four times a day. Other types of astragalus, including some that grow in the United States, have different components and could make you sick, according to NCCIH. Chin J Integr.Med 2006;12(1):29-31. Kobayashi, H., Mizuno, N., Teramae, H., Kutsuna, H., Ueoku, S., Onoyama, J., Yamanaka, K., Fujita, N., and Ishii, M. Diet and Japanese herbal medicine for recalcitrant atopic dermatitis: efficacy and safety. You can also brew it as a tea. Prieto JM, Recio MC, Giner RM, et al. Santa Cruz, CA: American Herbal Pharmacopoeia. Rev Neurol 2003;36:860-71. 2006;26(6):552-554. Wu, J. H., Li, Q., Wu, M. Y., Guo, D. J., Chen, H. L., Chen, S. L., Seto, S. W., Au, A. L., Poon, C. C., Leung, G. P., Lee, S. M., Kwan, Y. W., and Chan, S. W. Formononetin, an isoflavone, relaxes rat isolated aorta through endothelium-dependent and endothelium-independent pathways. View abstract. Your lithium dose might need to be changed. Though no dosage recommendation exists, up to 60 grams daily for up to four months appears to be safe for most people. Tian L, Ai J Deng C. Clinical observation of Huangqi injection combined with captopril for the treatment of 46 cases with chronic pulmonary heart failure. The curative effect of the treatment of chronic congestive cardiac deficiency by Astragalue injection and digoxin. View abstract. Roberts AT, Martin CK, Liu Z, et al. 1990;10(2):71-4, 67. A typical dose is 500 milligrams (mg) taken two or three times a day. Astragalus may interact with medications that suppress the immune system. Astragalus is an herb thats been used in traditional Chinese medicine for many centuries to boost the immune system. Qun L, Luo Q, Zhang ZY, et al. Be cautious of taking astragalus supplements if you have allergies to certain medications or foods. View abstract. Astragalus is used in traditional Chinese medicine for night sweats and diarrhea. Wu, J., Wang, Y. X., Su, W. L., Zhu, W. X., Lu, J. W., and Li, Z. K. Effect of astragalus injection on serious abdominal traumatic patients' cellular immunity. I call it wired but tired. It's when youre burnt out but a little anxious, she says. The root of the plant has been used as a medicine and diet supplement for thousands of years. Journal of Guangdong College of Pharmacy 2005;21(5):610-611. Zhongguo Zhong.Xi.Yi.Jie.He.Za Zhi. 500. 1992;12(11):669-71, 645. 2003;23(5):351-353. 2002;22(7):515-517. Historically and even today, they use it for chronic kidney disease, diabetes, heart health, adjunctive therapy during cancer, and as an adaptogen (stress support) among other ailments. Zhong.Xi.Yi.Jie.He.Xue.Bao. But these symptoms aren't normal or common at all. Yang H, Kang X. Zhongguo Zhong.Xi.Yi.Jie.He.Za Zhi. Brain Cogn 2009;71(3):354-361. Am.J.Chin Med. Immune restoration of local xenogeneic graft-versus-host reaction in cancer patients by fractionated Astragalus membranaceus in vitro. Chu G, Peng X. Astragalus injection as assisted treatment for refractory heart failure. Hong CY, Ku J, Wu P. Astragalus membranaceus stimulates human sperm motility in vitro. Hoo, R. L., Wong, J. Y., Qiao, C., Xu, A., Xu, H., and Lam, K. S. The effective fraction isolated from Radix Astragali alleviates glucose intolerance, insulin resistance and hypertriglyceridemia in db/db diabetic mice through its anti-inflammatory activity. Tibetan Medical Journal 2000;21(2):14-15. Zhao, X. View abstract. The treatment of 80 cases of intractable heart failure with traditional Chinese and Western medicine. Astragalus root can be taken in a standardized extract, tea or decoction, powdered root, tincture or ointment, all of which have their recommended dosages. Z. Clinical observation on effect of Radix Astragali treating 66 patients with viral myocarditis complicated with cardiac dysfunction. Liang, H. Y., Hou, F., Ding, Y. L., Zhang, W. N., Huang, X. H., Zhang, B. Y., and Liu, Y. Extract of astragalus membranaceus and ligustrum lucidum does not prevent cyclophosphamide-induced myelosuppression. Some medications, such as those used after a transplant, decrease the activity of the immune system. 2010;(1):CD006556. Burack, J. H., Cohen, M. R., Hahn, J. Weng, X. S. [Treatment of leucopenia with pure Astragalus preparation--an analysis of 115 leucopenic cases]. People sometimes use it on the skin for wound care. Z. Acta Otolaryngol. View abstract. Chen, H. 104 cases of acute viral myocarditis treated with Astragalus membranaceus injection. Wang, J., Zhang, Q. Y., and Chen, Y. X. [Clinical study of 96 cases with chronic hepatitis B treated with jiedu yanggan gao by a double-blind method]. 2012;11:CD003711. Modern Medicine & Health 2005;21(17):2337-2338. The earliest recorded references to astragalus are in the Chinese medical literature, dating from 400 to 200 B.C., according to the journal Aging and Disease. 2005;1-72. View abstract. If you want to keep the plant alive, only harvest 30% of the smaller roots. If you do experience any negative side effects, consider decreasing your dosage or discontinuing use. Xiao, H. B., Krucker, M., Albert, K., and Liang, X. M. Determination and identification of isoflavonoids in Radix astragali by matrix solid-phase dispersion extraction and high-performance liquid chromatography with photodiode array and mass spectrometric detection. Astragalus Extract ( 84687-43-4) is an important herb known for its many health benefits. Journal of Ethnopharmacology 1990;30(2):145-149. Zhongguo Zhong.Xi.Yi.Jie.He.Za Zhi. Zhong.Nan.Da.Xue.Xue.Bao.Yi.Xue.Ban. 2004;24(1):57-58. Chen, P. Y., Zhou, F., Chen, W. L., Ceng, Y., and Luo, L. Y. Phase IV trials are used to detect . 2008;28(6):495-498. View abstract. Sara Nuss is a University of Pittsburgh alumna with a passion for writing and journalism. Effect of Radix Astragali seu Hedysari on the interferon system. [Effects of Ailing Granule on immuno-reconstruction in HIV/AIDS patients]. He says it can make joint pain much worse in particular, there were other reasons for the contraindication. View abstract. Zhang, Z. X., Wu, L. L., and Chen, M. [Effect of lixu jieyu recipe in treating 75 patients with chronic fatigue syndrome]. J Int Soc Sports Nutr 2021;18(1):57. Here are 17 foods that you should likely avoid. Zhongguo Zhong Xi Yi Jie He Za Zhi 1994;14(3):142-144, 131-2. Persons taking any supplement or nootropic to impact sleep must be careful. Side effects of astragalus are uncommon but could include rash, itching, nasal symptoms, or an upset stomach. View abstract. Wang, H., Chang, B., and Wang, B. Traditional Chinese medicine holds that children with a fever should not take astragalus because it may increase the fever and result in it lasting longer. View abstract. Theres still limited research on astragalus, but it has uses in treating the common cold, seasonal allergies, heart conditions, kidney disease, chronic fatigue and more (5, 6). It has also been shown that astragalus supplements can help to protect your kidneys and be used to treat kidney disease. Speak to a doctor before giving astragalus supplements to a child. 2005;26(3):345-352. Astragalus has been found to interact with certain medications used to suppress immune function, according to the NCCIH. Dig and twist until a good portion of the root comes out. Similarly, astragalus supplements have been shown to help treat seasonal allergies like hay fever or allergic rhinitis. View abstract. Medicine Innovation Research 2008;5(2):102-103. If you continue to use this site we will assume that you are happy with it. 2004; Wang, H. Report of Clinical Trial of Compount Qishe Tablet: Phase III. Its important to keep in mind that when we talk about astragalus we are talking about the speciesAstragalus membranaceus. 4. May Support Immune Health. Astragalus ( Astragalus membranaceous) is an Asian plant that's been used medicinally for centuries. 2003;23(10):779-780. Liaoning Journal of Practical Diabetes 2002;10:34-35. If you suffer from insomnia, , or interrupted sleep patterns, regular consumption of astragalus root extract can quickly get you back into a healthy Circadian rhythm. View abstract. Astragalus. Shanghai Medical & Pharmaceutical Journal 1996;2:17-18. Journal of Chinese Practical Medicine 2000;2(9):72. Clinical research on Huangqi injection for congestive heart failure. Zhao, K. S., Mancini, C., and Doria, G. Enhancement of the immune response in mice by Astragalus membranaceus extracts. However, minor side effects have been reported in studies, such as a rash, itching, runny nose, nausea and diarrhea (2, 37). [Effects of Astragalus membranaceus on left ventricular function and oxygen free radical in acute myocardial infarction patients and mechanism of its cardiotonic action]. Zhang, T. Gu H. D. Han J. H. Application of Astragalus injection on 31 patients with diabetic nephropathy. Arch.Pharm.Res. 2001;21(3):171-173. It may also be injected in a medical setting., While there is still limited research on the health benefits of astragalus, it contains many active plant compounds that may be responsible for its healing properties, like strengthening the immune system and reducing inflammation., The compounds in astragalus may enhance and support your immune system. Gao, S. R., Bu, J. H., and Zhu, L. Z. This green powder is made with organic veggies that also helps to provide the energy that you need to get through the day and it is filled with adaptogens as well. Though research is limited, it may also help fight viral infections in humans, including the common cold and infection of the liver (11, 12, 13). View abstract. When consumed, adaptogens target stressors in the . View abstract. View abstract. View abstract. Astragalus contains beneficial plant compounds that may enhance your immune system. Medicine (Baltimore) 2019;98(11):e14798. View abstract. Lu Z, Zhao D Liu Y. View abstract. Astragalus may support kidney health by improving blood flow and laboratory markers of kidney function, such as measures of protein in the urine. Repressed exercise-induced hepcidin levels after danggui buxue tang supplementation in male recreational runners. Chinese Journal of Integrated Traditional and Western Medicine 2001;7(3):186-189. Preliminary report of a randomized, double-blind placebo-controlled trial of a Chinese herbal medicine preparation CH-100 in the treatment of chronic hepatitis C. Journal of Gastroenterology and Hepatology 1998;13(3):244-247. Astragalus could significantly reduce exercise-induced fatigue in oxygen-deprived mice and improved exercise performance in trained mice [ 3, 71 ]. Full paper database of Chinese excellent dissertations by doctors and masters 2009; Huang, C. L. and Lu, Y. P. [Effect of Astragalus injection on insulin resistance in auxiliary treating patients with diabetes mellitus type 2]. Astragalus (a traditional Chinese medicine) for treating chronic kidney disease. View abstract. 2011;6(5):e19604. Thromb.Haemost. Brunetti, L. and DeSantis, E. R. Treatment of viral myocarditis caused by coxsackievirus B. J Gastroenterol.Hepatol. While there are few risks of astragalus use, some side effects have been reported, including: Nausea Diarrhea Itching Rash Runny nose It may be safe for most people to use, but astragalus may. Z., Chen, R. Z., and Zhang, J. N. [Observation on collaborative treatment of dilated cardiomyopathy]. 1995;15(12):707-709. It may also help prevent infections in people with reduced kidney function (30). Liao, J. Henan Traditional Chinese Medicine 2005;25(10):78. Yang, S. P., Dong, H., and Wu, Y. C. [Clinical effect of milkvetch extract oral liquid in preventing and treating children's recurrent respiratory tract infection]. Zhongguo Zhong Xi Yi Jie He Za Zhi 1994;14(4):199-202. Try sublingual tablets (to be placed under the tongue and allowed to dissolve); take 2.5 mg at bedtime as an occasional dose, making sure that your bedroom is completely dark. Liu Y. Different foods can affect the function of your kidneys. You can connect with Sara on LinkedIn. With that said I see people who have chronic lyme take it, and it's in the AL Complex which I have just started again. 1990;103(8):647-651. Zuo, C., Xie, X. S., Qiu, H. Y., Deng, Y., Zhu, D., and Fan, J. M. Astragalus mongholicus ameliorates renal fibrosis by modulating HGF and TGF-beta in rats with unilateral ureteral obstruction. But at the same time it can make hot flashes and night sweats worse, and it can have unwanted effects on a hypersensitive immune system. Li, D. P., Chen, Q., and Yi, L. [Effects of yiqi huoxue method on cardiac function in patients with congestive heart failure]. It is high in antioxidants as well as antibacterial and anti-inflammatory properties. Doses of up to 60 grams taken by mouth daily for four months have been recorded without any negative impact. 2013 Feb;20(2):223-31. Liu, X., Yang, Y., Zhang, X., Xu, S., He, S., Huang, W., and Roberts, M. S. Compound Astragalus and Salvia miltiorrhiza extract inhibits cell invasion by modulating transforming growth factor-beta/Smad in HepG2 cell. Application of Astragalus injection on diabetic nephropathy complicated with chronic renal failure. Sleep-related side effects from fish oil, such as sleepiness or insomnia, don't occur commonly, and when they do they usually improve within a couple of weeks as your body adjusts to the influx of omega-3 fatty acids. Luo Q, Wang Y Hu M. Therapeutic effect observation of Astragalus injection with conventional therapy for 46 elderly patients with chronic congestive heart failure. Cha, R. J., Zeng, D. W., and Chang, Q. S. [Non-surgical treatment of small cell lung cancer with chemo-radio- immunotherapy and traditional Chinese medicine]. Yang Y. 2009;29(9):794-797. Systematic review and meta-analysis of 16 randomized clinical trials of radix astragali and its prescriptions for diabetic retinopathy. Zhongguo Zhong.Xi.Yi.Jie.He.Za Zhi. Sheng, Z. L., Li, N. Y., and Ge, X. P. [Clinical study of baoyuan dahuang decoction in the treatment of chronic renal failure]. Lu, D. C., Su, Z. J., and Rui, T. [Effect of jian yan ling on serum lipids, apoprotein and lipoprotein-a]. 2004;24(7):589-592. J.Med.Assoc.Thai. View abstract. Chongqing Medical Journal 2000;29(1):71-72. J Agric.Food Chem. View abstract. feeling "hangry"), or feeling "tired but wired", especially at night, you may have some level of adrenal dysfunction. The phase IV clinical study analyzes what interactions people who take Nac and Astragalus have. Thats because, according to the NCCIH, there are no high-quality human studies of astragalus for health conditions. J Ethnopharmacol. Astragalus can increase the activity of the immune system. Number of Warfarin sodium and Astragalus reports submitted per year: Common Warfarin Sodium and Astragalus drug interactions by gender *: female: Chronic kidney disease Renal injury When taken by mouth: Astragalus is possibly safe for most adults. View abstract. Modern Journal of Integrated Traditional Chinese and Western Medicine 2005;14(5):610. For example, 7.5-15 grams of astragalus taken daily for three to six months reduced the risk of infection by 38% in people with a kidney disorder called nephrotic syndrome. Park JH, Kim BK, Park MK, and et al. View abstract. View abstract. View abstract. View abstract. View abstract. View abstract. Heilongjiang Journal of Traditional Chinese Medicine 2004;3:8-9. [Clinical and experimental study of the effect of kang er xin-I on viral myocarditis]. 30 cases of infantile viral myocarditis treated by integrated Chinese and western drugs. Ying, L. H. Observation of the therapeutic effect of Astragalus injection on diabetic nephropathy. Proponents say it may also improve heart and kidney health and fight diabetes and cancer. It tends to be fairly well tolerated by most people who take it. View abstract. Yang, Q. Y., Lu, S., and Sun, H. R. [Effects of astragalus on cardiac function and serum tumor neorosis factor-alpha level in patients with chronic heart failure]. Wei, H., Sun, R., Xiao, W., Feng, J., Zhen, C., Xu, X., and Tian, Z. Chinese Journal of Emergency Medicine Integrated Chinese and Western Medicine 2001;8:283-1283. Our experts continually monitor the health and wellness space, and we update our articles when new information becomes available. Guo, Q. Y. Tang C. F. Fang X. H. Observation of the therapeutic effect of Astragalus injection on early stage of diabetic nephropathy. Menopause. 2011;11(2):142-148. Clinical observation of Huangqi injection for chronic congestive heart failure. J Ethnopharmacol 2019;239:111921. View abstract. Peng, M. H., Wang, X. Y., Sun, F. Y., Du, X. Zhongguo Zhong.Xi.Yi.Jie.He.Za Zhi. The clinical observation of Astragalus injection for congestive heart failure. Have you ever heard of astragalus? Doses of up to 60 grams daily have been safely used for up to 4 months. Li, N. Q. Liu Z. The overall long-term safety of ashwagandha is also unknown. For example, studies have shown that taking 4060 grams of astragalus per day has the potential to improve blood sugar levels after fasting and after meals in people with type 2 diabetes when taken daily for up to four months (27). View abstract. Zhonghua Er.Ke.Za Zhi. If you take any of the following medications, you should not use astragalus without first asking your doctor: Drugs that suppress the immune system: Astragalus may interfere with these drugs. View abstract. Meta-analysis of astragalus-containing traditional Chinese medicine combined with chemotherapy for colorectal cancer: efficacy and safety to tumor response. Zhongguo Zhong.Xi.Yi.Jie.He.Za Zhi. Journal of Traditional Chinese Medicine 1986;27(4):37-39. [11] This is perhaps the most important and popular use of astragalus, namely because everyone wants to live forever. Zhonghua Nan.Ke.Xue. 1993;13(5):269-60. Z., He, Y. Y., and Chen, G. [Clinical and experimental study on effects of man-shen-ling oral liquid in the treatment of 100 cases of chronic nephritis]. Therefore, take 200-400 mg of elemental magnesium per day, preferably as magnesium taurate or Jigsaw Magnesium, the most absorbable kinds. Du, W. T. Li F. M. The effect of Astragalus on improvement of renal injury in early stage of diabetic nephropathy. Here are some common negative reactions to ashwagandha: 1. J Nutr Biochem. Dai, C. F., Zhang, Z. Chinese Medical Journal 1990;103(4):304-307. Astragalus is used in traditional Chinese medicine for night sweats and diarrhea. A study on the immune receptors for polysaccharides from the roots of Astragalus membranaceus, a Chinese medicinal herb. 2009;29(4):313-316. Lee, T. M., Guo, L. G., Shi, H. Z., Li, Y. However, other studies in patients with heart failure have failed to demonstrate any benefits for heart function (17). Qian, Z. W., Mao, S. J., Cai, X. C., Zhang, X. L., Gao, F. X., Lu, M. F., Shao, X. S., Li, Y. Y., Yang, X. K., Zhuo, Y. In Traditional Chinese Medicine, astragalus is given following a heart attack to keep the blood fluid. In supplement form, however, it has been associated with some mild adverse symptoms. Acta Chinese Medicine and Pharmacology 1998;26(1):9-10. Xia, D., Zeng, Y., and Liao, Z. View abstract. Journal of Practical Emergency Medicine Integrated Chinese and Western Medicine 1999;6:230-231. What astragalus root extracts do is that they activate the enzyme known as telomerase. Its considered an adaptogen. So you should avoid using astragalus if you are taking immune-suppressing drugs. The dosage of astragalus root is different for adults and children. J Acquir.Immune.Defic.Syndr.Hum.Retrovirol. Pregnant or nursing women should not use astragalus root. Study on the effects of combined treatment with Radix Astragali injection for infantile viral myocarditis. View abstract. A Complete Scientific Guide, What Is the Anti-Inflammatory Diet? You can learn more about adrenal dysfunction, as well as how to address and treat it through an at-home protocol, . Some individuals may be allergic. View abstract. Chinese Journal of Integrative Medicine on Cardio-Cerebro Vascular Disease 2008;6:114-115. [Experimental study of the effect of Astragalus membranaceus against herpes simplex virus type 1]. Astragalus supplements may be a good option for you if you are looking for a natural, herbal way to treat certain medical issues, with the help of your physician. Consult your healthcare provider or herbalist for the correct dose for you. Journal of Practical Traditional Chinese Medicine 2004;20(9):501. Zhao, X. W. and Guo, C. Q. Kang qian wei in the treatment of chronic hepatitis B [in Chinese]. Summary Astragalus is generally well tolerated but should be avoided if you are pregnant or breastfeeding, have an autoimmune disease or are taking immunosuppressant drugs. 2005 - 2023 WebMD LLC. View abstract. Theres not much research on the safety or effectiveness of astragalus on the skin, but a study of human skin cells published in Aging and Diseasein December 2017 found that astragalus might protect against UVA rays. Shi, H. M., Dai, R. H., and Fan, W. H. [Intervention of lidocaine and Astragalus membranaceus on ventricular late potentials]. Zhong.Yao Cai. View abstract. Astragalus is considered an adaptogen. Fu, S., Zhang, J., Menniti-Ippolito, F., Gao, X., Galeotti, F., Massari, M., Hu, L., Zhang, B., Ferrelli, R., Fauci, A., Firenzuoli, F., Shang, H., Guerra, R., and Raschetti, R. Huangqi injection (a traditional Chinese patent medicine) for chronic heart failure: a systematic review. Zhong.Xi.Yi.Jie.He.Za Zhi. University of Maryland Medical Center; Astragalus; Steven D. Ehrlich; August 2008. 2012;14(5):344-349. View abstract. Wang H. Clinical research on Astragalus injection as assisted treatment for refractory heart failure. Tan, Y. But testing doesnt prove that a product is safe or effective. Lu, L. J., Zhao, D. Y., Li, S. Y., and Lin, Q. F. Clinical analysis of 179 cases of hepatitis B treated with Chinese herbal combination hepatitis B formula #3 [in Chinese]. Zhongguo Zhong.Xi.Yi.Jie.He.Za Zhi. Wang, G. L. Wei X. P. Observation of recent curative effect of Astragalus membranaceus injection on diagetic nephropathy. Upton R, ed. 2003;23(5):380-381. individual. View abstract. Germination takes place 3-10 days after sowing the seeds, but make sure you soak the seeds for at least one hour before planting to help soften the seeds and speed up the process. Is Astragalus an antiviral? Adaptogens are botanicals that help the body remain resilient in the face of stressors such as infection, illness, or mental, emotional, or environmental stress, says Kalea Wattles, ND, a naturopathic physician with the Institute for Functional Medicine in Washington state. There is no way to stop free radical cells at all, but astragalus is known to help with this issue., Astragalus can actually be taken in two different ways, orally, and through topical lotions on your skin, which can help to keep blood flowing throughout your body and even speed up the healing process of wounds that you may have.. 5 How does astragalus root extract help with sleep issues? Complement Ther.Med 2009;17(3):141-146. Its also used to help treat heart conditions, kidney disease and more. Chin J Integr.Med 2009;15(3):233-235. If you have an autoimmune disease, such as rheumatoid arthritis or lupus, or take cyclophosphamide, a medication used to reduce the chances of rejection in transplant recipients, or corticosteroids, do .